This film shows the correlation between fluid balance and pathologic processes, which is related to the existence and the metamorphosis of a viroid endobiont. Deviations from the normal body fluid environment inevitably cause cyclogenetic mutations in the endobiotic viroid microbe which then mutates from the symbiotic state to parasitical forms and thus indicates the degree of pathologic state. Filmed using the Ergonom microscope - a light optical research microscope which allows viewing of living unstained organisms non-destructively at a very high resolution and magnification with enhanced depth of field and color contrast using the Grayfield contrast method. Narrated by Peter Walker. Copyright 2003, Kurt Olbrich and Grayfield Optical Inc.
Note: The Ergonom 500 microscope shown here, has now been replaced by the SeeNano series which has comparable capabilities and more advanced electronics. All images are made in real time and natural colors without staining or oil immersion. Due to the extended working distance, the objective does not actually touch the slide at any time (max. NA 0.95).
Most images, with resolution of 200nm or greater, could have also been made with the SeeNano Lab series of microscopes. Like the SeeNano Pro, the Lab series also features enhanced DOF and full color contrast without the need for staining or oil immersion.